Returns and refunds

Unfortunately we cannot accept returns of prescription products for reuse or resale, and all sales are final. However, if you feel we have made an error in the filling of your prescription, please contact us at

Frequently asked questions

Have questions about Plenity? We've got answers.
Here are a few of our top FAQs.

When will I begin to lose weight?

Weight loss is a gradual process and every experience is different. In clinical studies, most people taking Plenity with diet and exercise had excess body weight loss over time that was significant at 4 weeks.

Dr. Mike Bohl

Medical Team at Ro

Do I need to be on a specific diet or exercise regimen when taking Plenity?

Having a reduced calorie diet with 30 minutes of daily physical activity is part of a healthy lifestyle. Plenity can work with any diet or nutrition plan and since Plenity makes you feel fuller, it can help you eat less.

Dr. Tzvi Doron

DO, Family Medicine
Medical Team at Ro

How does Plenity work?

When Plenity is combined with water, small Plenity hydrogel particles are formed. These hydrated hydrogel particles do not clump together, rather they mix with food and promote a sense of fullness.

Dr. Mike Bohl

Medical Team at Ro

Important Safety Information

  • Patients who are pregnant or are allergic to cellulose, citric acid, sodium stearyl fumarate, gelatin, or titanium dioxide should not take Plenity.
  • To avoid impact on the absorption of medications:
    • For all medications that should be taken with food, take them after starting a meal.
    • For all medications that should be taken without food (on an empty stomach), continue taking on an empty stomach or as recommended by your physician.
  • The overall incidence of side effects with Plenity was no different than placebo. The most common side effects were diarrhea, distended abdomen, infrequent bowel movements, and flatulence.
  • Contact a doctor right away if problems occur. If you have a severe allergic reaction, severe stomach pain, or severe diarrhea, stop using Plenity until you can speak to your doctor.

Rx Only. For the safe and proper use of Plenity or more information, talk to a healthcare professional, read the Patient Instructions for Use, or call 1-844-PLENITY.